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This ERK-without-Akt profile supports cellular proliferation and survival while maintaining cells in a proliferative rather than differentiated state contrasting sharply with IGF-1s PI3K/Akt/mTOR-dominant signalling, which drives protein synthesis and differentiation

Winter 2010;16(4):17-25

Induction of Wnt/-catenin pathway components, a putative mode of action of NTAPP, was commonly observed in both models, the HF organ culture and in vivo mouse skin

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An estimated 10-30% of adults over the age of 50 have difficulty absorbing vitamin B12 from food

Zhao, W., Zhang, J., Lu, Y