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For example, amphiphilic gold nanoparticles coated with hexanethiol and 11-mercaptoundecanesulfonic acid was used for the delivery of TLR7 ligands, as an immune stimulant for tumor lymph nodes, which can cause local immune activation and stimulate cytotoxic T cells to respond to tumors [74]

Continuing challenges are the incorrect, vague or ambiguous annotations in online gene databases, in addition to annotations based on older nomenclature thus does not easily correspond with current literature 41,45

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Nikolskaya et al., 2009

Conclusions: Although GPX3 may not directly influence immune checkpoint pathways, its high expression in myeloid cells and fibroblasts suggests that it might indirectly modulate immune responses by regulating the tumor microenvironment