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V.BurchardJ.MaoM.et al (2003)

Under physiological conditions, mitochondria generate a minimal amount of ROS via the electron transport chain (ETC)

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To overcome the limitations of high-dose systemic toxicity, the use of Se in the form of nanoparticles (SeNPs as elemental selenium (Se 0 )) has been investigated (Table 1), with initial promising results including SeNPs demonstrating preferential uptake by cancer cells [32, 33]