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BEACON Trial Investigators

Peptide MHC binding prediction Peptide binding predictions were performed by using NetMHCpan 4.1 31

Rivera-Chvez F, Zhang LF, Faber F et al (2016) Depletion of butyrate-producing Clostridia from the gut microbiota drives an aerobic luminal expansion of Salmonella

Consideration of a cyclical delivery of semaglutide, and other AOMs, could be considered, where semaglutide is administered until a pre-determined body weight is achieved, at which point an interval period is commenced until a pre-determined percentage of weight is regained, before restarting treatment

Building on this foundation, a strategic blend of prebiotics, probiotics, and postbiotics is designed to amplify butyrate the short-chain fatty acid that fuels and protects the colon