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Biol Trace Elem Res 199(5):20312046

The mice were switched to HFD 3 weeks after the injection and randomized into four groups with 11 mice in each group: normal, DEN/HFD + vehicle, DEN/HFD + RES, and DEN/HFD + NAC

this modulation helps maintain neurotransmitter stability (3)

Ferroptosis is characterized morphologically by mitochondrial volume reduction, cell swelling, and plasma membrane rupture, and is biochemically characterized by iron loading, lipid peroxidation, glutathione peroxidase 4 (GPX4) inactivation, and glutathione (GSH) depletion (Dixon and Stockwell, 2014