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8 Local anaesthetics also have a toxic effect on muscle cells, with greater damage again linked to higher concentrations and exposure

Dox pretreatment alone delayed the onset of ferroptosis (i.e., increased D O ) in response to erastin2 in Control cells capable of expressing p21, albeit not to the same extent as nutlin-3 treatment (Fig 2B and C)

Using genetic and pharmacological approaches in yeast, mammalian cells and Drosophila , we found that GPx activity robustly ameliorates Huntington's diseaserelevant metrics and is more protective than other antioxidant approaches tested here

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Zhou H, Wang Y, Zhang Y, Xiao Y, Liu X, Deng H, Lu X, Tang W, Zhang G (2022) Comparative analysis of heat-tolerant and heat-susceptible rice highlights the role of OsNCED1 gene in heat stress tolerance