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doi: 10.1016/j.chom.2015.05.005 102 HopfnerK-PHornungV

Other conditions associated with elevated B12 include: Chronic inflammatory states and autoimmune conditions Macro-B12 (B12 bound to immunoglobulins) causing laboratory assay interference without clinical significance Acute inflammatory responses Supplementation and medication should always be considered

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What Happens When You Dont Get Enough B12

Here's why that combination is interesting: rapamycin inhibits mTOR, the cellular growth pathway that, when chronically overactivated, drives cellular senescence in follicle stem cell niches