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These results track with existing in vivo, in vitro, and in silico evidence supporting GSHs role in maintaining redox homeostasis during diving in marine mammals [18, 20,21,22, 25, 26, 63]

88, 185191.10.1111/j.1651-2227.1999.tb14387.x 17 Camacho-HbnerC.WoodsK

doi: 10.1007/s11064-019-02837-x 169 LandenJWHauVWangMDavisTCiliaxBWainerBHet al

S.KwonW

Aug 2019;131(6):376-382

ALA, traditionally recognized for its antioxidant properties, indirectly attenuates ferroptotic signaling by enhancing glutathione concentrations and Nrf2 activity, which serves to inhibit iron-catalyzed lipid radical formation (92)