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Phase II neutralizes them by covalently attaching a conjugation group (glucuronic acid, glutathione, sulfate, acetyl, methyl, or amino acid) that increases polarity, reduces reactivity, and enables transport into bile or urine

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the cysteine conjugates PAP-CYS and APAP-CYS, were successfully prepared

The micro-needle component facilitates controlled disruption of the stratum corneum to enhance topical peptide absorption in dermatological research models

Another subject under investigation is its potential benefits in male and female infertility (12-14)