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The total combined duration of use of ketorolac tromethamine injection and oral ketorolac tromethamine is not to exceed 5 days of use because of the potential of increasing the frequency and severity of adverse reactions associated with the recommended doses (see WARNINGS, PRECAUTIONS, DOSAGE AND ADMINISTRATION, and ADVERSE REACTIONS)

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Ivashkiv & Donlin, 2014), which elicit potent antiviral activity (Isaacs & Lindenmann, 1957) by changing the cellular transcriptome and proteome (Trilling et al , 2013