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So you take a normal person

Preferential sorting to the constitutive pathway or the regulated secretory pathway has primarily been characterized in neurosecretory cell models (e.g., PC12 cells)

Researchers have studied it for decades in connection with aging, chronic illness, and cellular health

The reason neither of these panels are leading me to or away from my biotin hypothesis is that neither of them include serum biotin levels

However, these cells convert rapidly to a pro-regenerative phenotype (Ly6C lo ) [103] that is essential for recovery by removing cell debris and promoting regeneration [104, 105]

In this study, we were interested in exploring whether LA and LIAS levels were different among healthy subjects and SSc patients, and since DHLA has more antioxidant activity than LA, we examined if DHLA affects the profibrotic phenotype of dermal fibroblasts isolated from patients with diffuse SSc