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Immunoblotting was performed with 10 g of cytoplasmic and mitochondrial-enriched lysate as per the immunoblotting methods described below relative to whole-cell lysates

To further determine whether the protective effects of melatonin depend on STEAP3, we silenced STEAP3 using siRNA transfection in granulosa cells, treated them with DON, and then supplemented them with melatonin

doi: 10.1002/mds.27472 156 YoritakaA.TakanashiM.HirayamaM.NakaharaT.OhtaS.HattoriN

13.9 Anti-diabetic activity of curcumin Curcumin, known for its inflammatory and blood sugar-regulating properties, shows promise in preventing and managing type 2 diabetes

Although quercetin and metformin are found to possess antidiabetic activity in unison and their mechanism is found to be unclear, the combination therapy exhibits synergistic effects