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Imaging studies, such as computed tomography of the abdomen, should be carried out, as well as upper endoscopy, to rule out any obstruction at the level of the gastrointestinal tract (Fig

Conversely, PLCAR was found to be significantly more effective for alleviating general, physical fatigue and muscular weakness (p = 0.004)

Short-term treatment may provide targeted relief, however, combining antibiotics with probiotics can help reduce the harmful impact on the microbiota, while caution is suggested due to potential inflammatory responses [96102]

The accumulation and loss of epigenetic alterations in response to anticancer therapy may also provide temporary, plastic adaptations beneficial for survival (Gatenby et al., 2009

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