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To correct for paracellular leakage across the endothelial monolayer, the clearance quotient (CQ) of A was calculated using the following formula according to the previously described method 53 : AB direction: BA direction: The total fluorescence intensity of 5-TAMRA-A and FITC-inulin was defined as the sum of the fluorescence intensities measured in the apical and basolateral compartments

doi: 10.1038/s41564-018-0337-x

They consulted the Interferome database to calculate DNA Methylation Scores, indicating genes under the control of interferon (IFN)

However, even when combined with light microscopy, the tissue of origin can be identified in only ~30% of CUP cases ( Similarly, in this patient, the primary origin of the tumor could not be identified despite a comprehensive evaluation that included patient history, physical examination, blood analyses, contrast-enhanced CT, histopathology, and immunohistochemistry

(2) R Green, L H