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Consent for publication All the authors agreed to publish this study in Scientific Reports

Potential heterogeneity was explored with inverse-variance weighted meta-regression analyses and subgroup analysis

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Previous studies have shown that Forsythia suspensa extract can improve oxidative damage in broiler breast muscles, and the combination of cinnamon and probiotics can regulate oxidative stress and alleviate kidney toxicity in broilers (32, 33)

Overall, the preclinical package detailed above will support the initiation of a Phase 1/2 study, with first patient dosed planned for Q4 2024

Note: If you choose to use both, start one at a time