bacterial and host-derived glutathione are required to activate prfa Frontiers Glutathione activates virulence gene expression

Glutathione activates virulence gene expression of an intracellular pathogen Nature Glutathione Provides a Source of Cysteine Essential for Intracellular Multiplication of Francisella tularensis PLOS Pathogens Host glutathione is required for Rickettsia parkeri cell division and intracellular survival Nature Communications RCSB PDB 5LRS: The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione and a 30 bp operator PrfA box motif Discovery of a glutathione utilization pathway in Francisella that shows functional divergence between environmental and pathogenic species: Cell Host & Microbe The Role of the Glutathione System in Stress Adaptation, Morphogenesis and Virulence of Pathogenic Fungi

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