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Without deliberate effort to preserve muscle, the resulting body composition after major weight loss can be disappointing despite excellent scale results

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DNMT1 activity assay A radiometric assay was performed by RBC using 100 M 5 nM SAH as an inhibitor positive control

A 12-week Phase IIa trial involving 300 participants showed modest reductions in weight (2.6 kg versus 0.8 kg for placebo)

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