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B12 injections may also be useful for those with gastrointestinal issues, older adults, vegans, vegetarians, and people with underlying health conditions that can restrict vitamin B12 absorption

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Several RNAi drugs, including aptamers like pegaptanib targeting protein targets, and micro interfering RNAs like givosiran and patisiran, as well as antisense oligonucleotides like golodirsen and inotersen that interfere directly with RNA targets, have received FDA approval for medical use (Yu et al., 2020)

If you're leaning towards mornings, you might find useful keeping your vitamin B12 supplements right next to your bed or in your bathroom's medicine cabinet, so that you can get a daily visual cue that will make taking vitamin supplements in the morning as easy as remembering to brush your teeth

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Acknowledgements We wish to thank our collaborators (Drs