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Sound is also embarking on a Phase II study of SPI-1005 to prevent the ototoxicity, or drug-induced hearing loss, that affects people like Hirko

YZ: Writing original draft, Writing review and editing

Plant Foods Hum Nutr 78 , 493505 (2023)

Additionally, hepatotoxicity is a notable concern, particularly in patients with risk factors such as alcohol consumption, obesity, and diabetes, which can exacerbate liver damage

doi: 10.1007/s10803-022-05784-9 107 PaganoG.LyakhovichA.PallardF

Moving forward, establishing consensus protocols for sample processing, assay selection, data normalization, and reporting standards is essential for validating mtDNA-based biomarkers