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Where it binds In peer-reviewed studies, the peptide interacts with receptors on blood-vessel cells (VEGFR-2) and shifts the enzymes that produce nitric oxide (eNOS / iNOS)

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Determining the signaling pathways and molecular players that regulate NET release is therefore critical, not only for advancing our understanding of neutrophil biology but also for identifying new therapeutic targets to treat disorders associated with aberrant NETosis

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Mnard O, Cattenoz T, Guillemin H et al (2014) Validation of a new in vitro dynamic system to simulate infant digestion