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O.DaramolaM

Although initially studied in cancer contexts, the functional significance of lactylation has rapidly expanded to non-malignant pathologies characterised by inflammatory and fibrotic pathology, such as diabetic nephropathy [12]

ME2 overexpression increases pyruvate and NADH production while decreasing the cells NAD + /NADH ratio

The study also cross-references findings from a Norwegian cohort study in which removal of amalgam fillings produced a significant long-term decrease in blood inorganic mercury concentrations