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To achieve improved half-life, the inclusion of chemical modifications such as the use of D-amino acids, non-natural amino acids (e.g., ornithine), PEGylation and N and C-terminal modifications have been extensively employed

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200960 Suppl 7161-5

At 25 mg/mL, the single 50 mg vial contains enough for the full 30-day cycle at both dose levels

Meanwhile, nude mice were used as models to trace Tf-CPP-SSL in vivo, demonstrating this drug delivery system performed well in brain targeting and prolonged circulation

Preparation and comparison of tacrolimus-loaded solid dispersion and self-microemulsifying drug delivery system by in vitro / in vivo evaluation