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Intrinsic factor is crucial for the normal absorption of B12, therefore, a lack of intrinsic factor, as seen in pernicious anemia, causes a vitamin B12 deficiency

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Astrocyte- and neuron-derived extracellular vesicles from Alzheimers disease patients effect complement-mediated neurotoxicity

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Hepatic dysfunction can ultimately result in reduced production of coagulation factors, causing an enhanced response to warfarin and increased risk of bleeding