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For the synthesis of secondary metabolites and signaling molecules, several amino acids can act as precursors, for instance, polyamines are derived from Arg [21], Met synthesized the plant hormone ethylene [22], and conversion of Lys to N-hydroxy pipecoline is necessary for immune signaling [17, 23]

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Golizeh M, Lee K, Ilchenko S, Osme A, Bena J, Sadygov RG, et al

Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study

Supplementary data Figure S1

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