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For example, 200300 mg/d of selenite supplementation, selenium-enriched yeast or high dietary selenium intake did not have a positive effect on sperm characteristics or activity, in spite of increased semen selenium concentrations (Reference Mistry, Pipkin and Redman66)

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[7] [9] Patients with a history of oxalate nephrolithiasis (kidney stones) or hyperoxaluria should avoid high-dose vitamin C administration, as ascorbic acid is metabolized to oxalate, which may precipitate stone formation or exacerbate renal impairment

This leads to a mitochondrial benefit of better ATP production, [10,11] but also greater work output, recovery, lower perceived exertion, and reduced soreness

doi: 10.1038/s41586-021-03692-z 119 KawashimaKFujiiT

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