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Subcutaneous injection Subcutaneous injection is the most common administration route for peptides used systemically

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However, chitosans pH solubility profile limits its application in the small intestine, and its marine origin, batch variability, and limited GMP-grade availability restrict translational development (Li et al., 2025)

In extreme cases, it may cause post-inflammatory hyperpigmentation wherein the color may become darker than its natural tone

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Turk J Bot 43(6):74957 Kodzius R, Kojima M, Nishiyori H, Nakamura M, Fukuda S, Taqami M et al (2006) CAGE: cap analysis of gene expression