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Ethics declarations Ethics approval and consent to participate This study protocol was approved by the Ethics Committee of Shiraz University of Medical Sciences and performed in accordance with the Ethical Standards laid down in the 1964 Declaration of Helsinki and its later amendments

Consistent with expectations, this study confirmed that VPA is associated with a markedly increased risk of HE (ROR = 122.14), thereby reinforcing the hypothesis of a robust correlation between VPA and HE, thereby affirming the reliability of the FAERS database

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It is also important for mental functions, muscle coordination and the like nerve functions

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Probiotic Bifidobacterium lactis V9 Regulates the Secretion of Sex Hormones in Polycystic Ovary Syndrome Patients through the Gut-Brain Axis