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It could be shown that glycolysis in ECs is mainly regulated by PFKFB3 ( in vivo in an EC-specific Pfkfb3 -deficient mouse model, demonstrating that the lack of Pfkfb3 results in decreased branch points and sprouts in a postnatal retina model ( 6.1.2 Pentose phosphate pathway Besides the use of glucose as energy source, it can also be phosphorylated by hexokinase 2 to generate glucose-6-phosphate, which subsequently can be stored as glycogen or further processed in the PPP to yield NADPH (Mann et al., 2003

Mechanistically, non-small cell lung cancer (NSCLC) cells exhibit enhanced BCAAs uptake (Mayers et al., 2016)

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C1q is present at all embryonic developmental stages ( Figure 3 ) (306)

Furthermore, in sepsis models, BAM15 polarizes macrophages toward anti-inflammatory phenotypes and reduces pro-inflammatory cytokine production via AMPK-SIRT1-PGC1 axis activation (Dang et al., 2021)

Sertoli cells, as the only somatic cells that directly interact with developing germ cells, can form the blood-testis barrier (BTB) and have been described as key drivers of spermatogenesis [11]