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Food-first approach: Supplements supplement diet, dont replace it

[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Asnicar F, Berry SE, Valdes AM, Nguyen LH, Piccinno G, Drew DA, et al

The medication is contraindicated in patients with uncontrolled hypertension, seizure disorders, or current use of MAO inhibitors

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[1] [2] This triple-receptor mechanism distinguishes it from currently approved agents such as semaglutide (a GLP-1 agonist) or tirzepatide (a dual GIP/GLP-1 agonist)