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5.1.3 mGluR4 and immune cells The activation of mGluR4 can regulate the Th17 immune response

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This result highlights a cooperative and enhanced antiproliferative effect when curcumin and gemcitabine are used in tandem, especially in gemcitabine-resistant CCA cells

Lechien JR, Chiesa-Estomba CM, De Siati DR, Horoi M, Le Bon SD, Rodriguez A, et al

Such a pharmacological profile would be advantageous, particularly in view of the emerging link between chronic inflammation and cancer, where mPGES-1 and 5-LO may act as potential players

The study also showed that AC partially controls the expression levels of MAPK1, MAPK8, and MAPK14 to provide neuroprotective effects in PD models