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BPC-157 emerged from Croatian gastroenterology research into cytoprotection the idea that gastric juice contains substances that protect and heal the stomach lining

Shapiro, Michael J

PMCID: PMC6320789

10.1046/j.1471-4159.2001.00383.x J

GSNO has also been implicated as a contributor to various disease states

Strongest human evidence The METAOD006 (OPTIONS) Phase 2b trial randomized 502 adults with obesity (BMI 30-45 kg/m^2) to oral AOD-9604 (0.25, 0.5, or 1 mg/day) or placebo for 24 weeks alongside a supervised diet and exercise program