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A 12.5mcg dose isnt enormous, but it may help stave off deficiency, which has been associated with things like decreased testosterone levels.22 That all makes for a much more robust formula than the simple creatine-only offerings from Naked and Swolverine, but its not quite as comprehensive as the recovery formula from Nutrabio

HYGIENE A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS A61P7/00Drugs for disorders of the blood or the extracellular fluid A61P7/06Antianaemics AHUMAN NECESSITIES A61MEDICAL OR VETERINARY SCIENCE

Metabolic activation of flavin monooxygenase-mediated Trimethylamine-N-Oxide formation in experimental kidney disease

10.1016/j.bbamem.2016.10.002 119 McCannP.KruochZ.LopezS.MalliS.QureshiR.LiT

This suggests that a skatole metabolite is responsible, at least in part, for AhR activation, or is a more potent AhR activator than skatole