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Using an ERE-luciferase mouse, a reporter mouse that allows monitoring of ER transcriptional activity in a spatiotemporal manner, it was demonstrated that estrogen signaling is locally activated in keratinocytes in vitro (with 1 nM E2) and in vivo (with 10 nM E2)

Chidamide (CHI), a histone deacetylase inhibitor, diminished breast cancer growth and metastasis, enhanced ULK2-mediated autophagy, and increased cellular sensitivity to DOX-induced apoptosis, indicating its potential application in combating chemoresistance (145)

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Hill HA, Qi X, Jain P, Nomie K, Wang Y, Zhou S, Wang ML Genetic mutations and features of mantle cell lymphoma: a systematic review and meta-analysis

doi: 10.1038/s41430-023-01358-9 73

doi: 10.1186/s12883-021-02257-x, 43