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Nutrition 2018;53:120-33

One possible interpretation is that p53 may act as a monitor of the intracellular copper concentration, on the one hand, to maintain a proper physiological copper level by preventing accumulation of excessive labile copper, and on the other hand, to eliminate copper-damaged cells when the uptake or level of copper is pathologically or experimentally upregulated

In addition, this growth factor directly affects neuronal cells, and dysregulation of its expression has been implicated in several neurodegenerative diseases [172]

3.3 Platinum-based nanomaterials Platinum drugs, including cisplatin, oxaliplatin, and carboplatin, play an indispensable role in current cancer treatments

The MCC-Spain study enrolled 351 cases of stomach cancer and 3629 population-based controls between 2008 and 2013 and assessed consumption of aspartame-containing products as low- or no-calorie soft drinks and tabletop sweeteners other than saccharin (Palomar-Cros et al., 2023)

When a subgroup analysis was performed on only patients with NAFLD, female sex, absence of central obesity, and non-obesity were significant factors related to increased risk of plaque progression risk in sarcopenic patients