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Electron microscopy performed in aged non-human primates and rodents have further clarified this deterioration by revealing the structural alterations present in the myelin sheath, such as redundant myelination and reduced myelin thickness (Figure 1

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In the following sections we briefly discuss the identified proteins that were found to be altered upon neuronal tianma stimulation and we hypothesize potential applications of tianma that may emerge from our data obtained: Increased neuro-protective protein levels in differentiated neuronal N2a cells upon tianma activation Nxn : Nucleoredoxin is a novel thioredoxin family member that is involved in cell growth and differentiation where it sustains Wnt/-catenin signalling by retaining a pool of inactive dishevelled protein [27-29]

Glutathione can protect important cellular components from damage caused by reactive oxygen species, such as free radicals, peroxides, lipid peroxides, and heavy metals

Lang, S