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miltiorrhiza (Danshen), significantly inhibits the EMT process in silica-induced pulmonary fibrosis models by suppressing the TGF-1/Smad signaling pathway ( In vitro studies demonstrated that Tan IIA treatment increased nuclear expression of Smad7, inhibited Smad2 and Smad3 phosphorylation by TR1, and reduced the nuclear accumulation of phosphorylated Smad3, thus impeding ECM biosynthesis and myofibroblast differentiation

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It is vital to note that TB-500 is not a naturally occurring compound

In post-menopausal women, there is a decrease in estrogen resulting in saggy tissue and reduction in skin elasticity

Digestion was stopped by the addition of formic acid (FA) to a final concentration of 0.5%

The GSH level was higher ( p 0.001) in T2_HS as compared to T1_HS, CON, and CON_HS