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Our results establish a chemistry-based framework for engineering sustained covalent inhibition without accumulating permanently modified proteins and peptides

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Conversely, the inhibition of ferroptosis might not only inhibit the progression of endometriosis, but also improve the adverse effects of iron overload on ovarian function, thereby improving fertility and becoming a therapeutic approach for endometriosis-related infertility [128]

3.1.3 Phospholipid oxidation products and inflammatory signaling Oxidized phospholipids generated through peroxidation, such as hydroxylated lipids and keto-lipids, not only compromise the integrity of the cell membrane directly but also increase membrane tension in tandem with enhanced lipid peroxidation

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