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Furthermore, during aging nave T-cells show multiple alterations, including the shortening of telomeres, the reduced production of IL-2 and the diminished ability to differentiate themselves into effector-cells

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doi: 10.1001/jama.2010.1913

Cell death is of essence in the process of development, homeostasis, and pathogenesis of acute and chronic diseases, which tends to be accompanied with inflammation dysregulation, cell dysfunction, and tissue damage [12]

For example, Omniscan, Magnevist, OptiMARK, and Gadavist/Gadovist cause nephrogenic systemic fibrosis