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Metabolic and physiologic effects from consuming a hunter-gatherer (Paleolithic)-type diet in type 2 diabetes

Published research using these models has documented compound effects on histological joint scores, gait analysis parameters, inflammatory biomarker profiles, and cartilage preservation metrics

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Harris GS, Kozarich JW

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The accumulated evidence over recent decades regarding the efficacy of new pharmacological treatments for obesity has positioned the glucagon-like peptide-1 (GLP-1) analogue as a key componentwhether as monoagonists, unimolecular multiagonists, or in combination therapies targeting multiple receptors.1 These drugs have made it possible to achieve previously unthinkable goals in terms of weight reduction and control of various obesity-related comorbidities (Fig