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Grinshpun, Aerosolization of particulate (13)--D-glucan from moldy materials, Applied and Environmental Microbiology, vol

Guo et al , 2003

Free iron is reactive and dangerous to cells, and NRF2 regulates the expression of ferritin heavy and light chains (FTL and FTH1), which immediately bind free iron, as well as ferroportin, which exports it [79]

These effects were rescued by addition of N -acetylcysteine (NAC), which restored spheroid morphology, cell viability, and the death ratio to levels comparable with those in the control group (Fig