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Pept., 120, 215-225 22

This is further supported by the lack of Bip upregulation, a hallmark feature of ER stress (Fig

Duarte AR, Costa MS, Simplcio AL, et al

Luo et al., 2025)

Salze GP, Davis DA

While these trials span a diverse array of molecular targets and cancer types, a closer inspection reveals recurring obstacles that have limited their clinical success