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Per the American Diabetes Association (ADA) Standards of Care in Diabetes2026, diagnosis is confirmed by one of four criteria: fasting plasma glucose 126 mg/dL, 2-hour plasma glucose 200 mg/dL during a 75-g OGTT, A1C 6.5% (using an FDA-approved CLIA-certified method), or a random plasma glucose 200 mg/dL in a patient with classic hyperglycemia symptoms

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[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Hu J., Sang J., Hao F., Liu L

Recent studies have revealed that the mutual inhibition of Cyclin D1 and hepatocyte nuclear factor 4 (HNF4) harmonizes to regulate the progression of the cell cycle and metabolism within the liver

Those at greatest risk include: pregnant women

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