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For example, intradiscal injection of bone morphogenetic protein-2 (BMP-2) induced degenerative changes [92] and weekly intradiscal treatment with growth and differentiation factor-5 (GDF-5) or insulin-like growth factor-1 (IGF-1) resulted in inflammatory reactions in the adjacent vertebrae and connective tissue infiltrates in the NP, causing the IVD to collapse [93]

Guo P, Wang W, Xiang Q, Pan C, Qiu Y, Li T et al

Enhanced angiogenic effects of GHK peptides and Cu in extracellular matrix models

While phosphorylation at Ser616 enhances fission activity, phosphorylation at Ser637 exerts an inhibitory effect under physiological conditions (Serasinghe and Chipuk, 2017)

Genome-wide identification and analysis of the GGCT gene family in wheat

Larsen C, Winther KH, Cramon PK, Rasmussen K, Feldt-Rasmusssen U, Knudsen NJ, Bjorner JB, Schomburg L, Demircan K, Chillon TS, Gram J, Hansen SG, Brandt F, Nygaard B, Watt T, Hegedus L, Bonnema SJ