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Functional pathway analysis revealed transcriptional levels were mainly related to immune response, metabolic process and cytokine signaling

A well-characterized example of this mechanism is the Keap1Nrf2 signaling axis, illustrated in Fig

Further inter-species microglial differences in gene-expression include the alteration of AD risk genes such as SORL1, CHI3L1, and -2 macroglobulin in human AD patients, but not in 5xFAD mice (Zhou et al., 2020)

FAO is critical to ensure a continuous supply of acetyl-CoA for the TCA cycle and NADH/FADH 2 for the electron transport chain, particularly during increased energy demands such as exercise or fasting

Results: The study cohort included 67 (19.6%) patients with LSM 10.5kPa

One mL of the sample solution was mixed with 1 mL of metal solution followed by the addition of 0.1 mL of 1 mM tetramethylmurexide solution