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This was associated with an increase in bile acid synthesis pathways and a trend towards greater cholangiocyte signature (Figure 1) in BA1 compared to BA2

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7 Evidence-based mitigation strategies 7.1 Pre-cooking interventions: antioxidant marinades and pH modification 7.1.1 Mechanistic basis for marination effects Marinating meat or fish before high-temperature cooking represents one of the most practical and scientifically validated approaches for reducing carcinogen formation