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doi: 10.1172/JCI10196 197 ZhangWChoiJZengWRogersSAAlyeaEPRheinwaldJGet al

Given the pivotal role of macrophages in the pathogenesis of CVDs, a variety of targeted therapeutic strategies have been developed

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Most community protocols run the combined stack for 16-24 weeks before evaluating results and either continuing, tapering, or moving to maintenance

This consumption of NO not only depletes bioavailable NO from the follicular and oocyte microenvironment but results in the over-production of harmful nitration products such as NO 2 - , NO 3 - , and ONOO - [27]