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Genetic and Functional Basis for Formaldehyde Detoxification via Glutathione-Dependent Pathways Amongst the three pathways for the detoxification of formaldehyde, the GSH-dependent pathway is the most widely distributed in the biological world, with examples from bacteria, plants, and mammals (Uotila and Koivusal, 1974a

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Cell Metab 34(7):969977 Lonardo A, Nascimbeni F, Targher G, Bernardi M, Bonino F, Bugianesi E, Casini A, Gastaldelli A, Marchesini G, Marra F, Miele L (2017) AISF position paper on nonalcoholic fatty liver disease (NAFLD): updates and future directions

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Portillo-Carrasquer M, Sanz-Alczar A, Snchez-Lpez B, Delaspre F, Pazos-Gil M, Oliveira-Jorge L, et al

As excessive ROS formation contributes to lipid peroxide generation 15 , we measured intracellular ROS levels following HO challenge and observed that MK-7 reduced ROS levels at 10 M (Fig