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Furthermore, our previous animal experiment demonstrated that glutathione enhances mitochondrial biogenesis by increasing peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1), 4 which is increased by exercise and enhances mitochondrial biogenesis

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In contrast, upregulation of TXN is associated with an increased resistance to cisplatin in other cell lines [148, 149]

Chen, Q., Qiao, Y., Xu, X

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doi: 10.1089/ars.2013.5278 15 FrovaC