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Patients, Material, and Methods Between 2015 and 2016, 66 patients with ME/CFS were studied ( The usual care of the study participants included a detailed clinical history, physical examination, vitamin B12 serum levels (pmol/l), and ECG and echocardiography

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8,9 Additionally, the anti-CD38 antibody isatuximab was evaluated in the ICARIA-MM study, in which patients with multiple myeloma who had received multiple lines of therapy were randomized to receive (1) pomalidomide/dexamethasone/isatuximab or (2) pomalidomide/dexamethasone

To remove excess cholesterol, Scavenger Receptor Class B Type I (SR-BI) on the liver selectively mediates uptake of cholesteryl esters from HighDensity Lipoprotein (HDL), thus moving cholesterol from peripheral tissues back to the liver