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Lactate that is produced from an oxygen-independent metabolic pathway (glycolysis) is shuttled to various tissues including muscle, heart, and brain, where it is used as a substrate for oxygen-dependent energy production

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If you dosed 5-Amino-1MQ at 8am and it's now 3pm (7 hours), taking MOTS-c still provides some benefit but misses peak NNMT inhibition

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They also found that capsaicin did not evoke inflammation after degeneration of the sensory nerve